Clinical trial · Interventional
Intervention to Motivate Standing &Walking in Gastrointestinal Cancer Surgical Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Observational research has linked physical activity with faster recovery, improved quality of life, and greater survival; however, little is known about the effects of physical activity in pre-operative, peri-operative, or post-operative treatment contexts and there is a need for interventions to improve patient outcomes across the cancer treatment continuum. Three propositions derived from basic research, epidemiological evidence, and clinical practice informed our intervention development efforts: (1) Patient outcomes will be enhanced by interventions that increase physical activity (i.e., standing, walking) across the cancer treatment continuum (i.e., pre-operative, peri-operative, post-operative). (2) Reducing sedentary behavior (i.e., seated or reclined activities involving minimal energy expenditure) will enhance patient outcomes both by increasing physical activity and by stimulating additional adaptive physiological responses to reduced sedentary time (responses which are independent of physical activity-induced responses). (3) Patients with gastrointestinal cancers often suffer functional limitations that limit their independence and their health behaviors are strongly influenced by the family environment so interventions that engage caregivers (e.g., spouses) will be more effective than those that target patients/survivors alone.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastrointestinal Neoplasms | Digestive System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Education/Daily Planning | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Education/Daily Planning
- description
- Physical Activity Education and Daily Planning Tool
- interventionNames
- Behavioral: Education/Daily Planning
- type
- NO_INTERVENTION
- label
- No Education/Daily Planning
- description
- No Physical Activity Education/ Daily Planning Tool
Primary outcomes (1)
- measure
- Percentage of patients with diagnosed gastrointestinal cancer who showed daily compliance using activity monitors and tablet computers to measure physical activity.
- timeFrame
- up to 1 year
- description
- To demonstrate the feasibility and acceptability of using activity monitors and tablet computers to measure physical activity (standing, walking)/sedentary behavior (sitting) and deliver daily interventions in this patient population, we will evaluate daily compliance using activity monitors and tablet computers.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of gastrointestinal tract cancer (hepatobiliary) requiring surgical resection. for treatment * Failing to meet the aerobic component of national physical activity guidelines over past week (e.g., \< 150 min moderate-intensity physical activity or \< 75 min vigorous-intensity physical activity). * Excessive sedentary behavior over the past week (\> 8 hrs/day sitting). * Minimum age 18 years. * A spouse or adult child serving as a caregiver who is also willing to participate. Exclusion Criteria: * Functional limitations that preclude normal physical activity. * Patients who will be scheduled for surgery \< 10 days after their clinic visit. * Medical contraindications to physical activity.
References
Publications (9)
- BACKGROUNDBallard-Barbash R, Friedenreich CM, Courneya KS, Siddiqi SM, McTiernan A, Alfano CM. Physical activity, biomarkers, and disease outcomes in cancer survivors: a systematic review. J Natl Cancer Inst. 2012 Jun 6;104(11):815-40. doi: 10.1093/jnci/djs207. Epub 2012 May 8. PMID 22570317
- BACKGROUNDLynch BM. Sedentary behavior and cancer: a systematic review of the literature and proposed biological mechanisms. Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2691-709. doi: 10.1158/1055-9965.EPI-10-0815. Epub 2010 Sep 10. PMID 20833969
- BACKGROUNDSantos DA, Silva AM, Baptista F, Santos R, Vale S, Mota J, Sardinha LB. Sedentary behavior and physical activity are independently related to functional fitness in older adults. Exp Gerontol. 2012 Dec;47(12):908-12. doi: 10.1016/j.exger.2012.07.011. Epub 2012 Aug 1. PMID 22884978
- BACKGROUNDCarlson SA, Fulton JE, Schoenborn CA, Loustalot F. Trend and prevalence estimates based on the 2008 Physical Activity Guidelines for Americans. Am J Prev Med. 2010 Oct;39(4):305-13. doi: 10.1016/j.amepre.2010.06.006. PMID 20837280
- BACKGROUNDMatthews CE, Chen KY, Freedson PS, Buchowski MS, Beech BM, Pate RR, Troiano RP. Amount of time spent in sedentary behaviors in the United States, 2003-2004. Am J Epidemiol. 2008 Apr 1;167(7):875-81. doi: 10.1093/aje/kwm390. Epub 2008 Feb 25. PMID 18303006
- BACKGROUNDSchwarzer R, Lippke S, Luszczynska A. Mechanisms of health behavior change in persons with chronic illness or disability: the Health Action Process Approach (HAPA). Rehabil Psychol. 2011 Aug;56(3):161-70. doi: 10.1037/a0024509. PMID 21767036
- BACKGROUNDGonzalez M, Guillaume JE, Laloux P, Mahieu P, Installe E. Strychnine poisoning, hypoxic damage, severe acidosis: a case report. Acta Clin Belg Suppl. 1990;13:94-5. No abstract available.