Clinical trial · Observational
Study of Esophageal Squamous Dysplasia Prevalence at Tenwek Hospital
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Esophageal squamous cell cancer (ESCC) is common in the developing world, and is the leading cancer diagnosis at Tenwek Hospital in southwestern Kenya. The investigators long-term goal is to understand the pathogenesis and risk factors for ESCC in Kenya, and to establish effective screening and prevention programs. The investigators hypothesize that asymptomatic esophageal squamous dysplasia (ESD) is common in their region, and the current protocol is designed to determine the prevalence of ESD in residents of southwestern Kenya.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Dysplasia | Esophageal Intraepithelial Neoplasia | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Percentage rate of subjects with Esophageal Squamous dysplasia calculated as Prevalence
- timeFrame
- 2 years
Secondary outcomes (3)
- measure
- percentage of subjects with severe esophageal squamous dysplasia calculated as a prevalence
- timeFrame
- 2 years
- measure
- percentage of subjects with moderate esophageal squamous dysplasia calculated as a prevalence
- timeFrame
- 2 years
- measure
- percentage of subjects with mild esophageal squamous dysplasia calculated as a prevalence
- timeFrame
- 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 20 years * No dysphagia (subjects will be asked "do you have trouble swallowing food or water? Do they get stuck inside after you swallow?" in their primary language Exclusion Criteria: * Cardiac, respiratory, or metabolic disease that would increase the risk of endoscopy: history of myocardial infarction, arrhythmias, chronic obstructive pulmonary disease, diabetes, allergy to lidocaine. * Unable or unwilling to provide informed consent.
References
Publications (0)
Data not yet available