Clinical trial · Interventional
Harmonics-based in Vivo Optical Virtual Biopsy
NCT01980264CI-TRIAL-00079975unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The research aims to study the molecules and structures in human skin by the image formation of harmonic-based in vivo optical virtual biopsy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diseased Participants With Different Skin Types and Different Ages | — | UNRESOLVED | — |
| Healthy Participants With Different Skin Types and Different Ages | — | UNRESOLVED | — |
| Participants Suffered From Diabetes With Different Skin Types and Different Ages | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Harmonic Generation Microscopy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Diagnostic imaging
- description
- Harmonic Generation Microscopy
- interventionNames
- Device: Harmonic Generation Microscopy
Primary outcomes (1)
- measure
- To noninvasively provide real-time imaging of cutaneous histopathology and molecular changes.
- timeFrame
- one year
- description
- To observe some analyzed molecule (melanin density, HbA1c density, collagen density, etc) \& structure (cell size, cell height, height of rete ridges, layer thickness, etc) parameters for different skin types \& age groups. (the information above can be observed in the nonlinear images) (Cell or molecule density is defined as the cell or molecule numbers in the specific image area) (Structure can be observed and reconstructed via multiple z-depth images)
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: 1. healthy volunteers of different skin colors and different ages 2. patients with suspected melanoma 3. patients with suspected basal cell carcinoma or squamous cell carcinoma 4. patients with diabetes mellitus Exclusion Criteria: 1. volunteers have infectious disease 2. volunteers' skin have been infected with ulceration
References
Publications (0)
Data not yet available
No reference posted for this study.