Clinical trial · Observational
Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia
Impact of Washed Transfusions in Adult Patients With Acute Myeloid or Lymphoid Leukemia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- Survial Rate at 30 Days
- timeFrame
- 30 days
- description
- The percentage of patients who were alive at 30 days after transfusion.
- measure
- Survial Rate at 60 Days
- timeFrame
- 60 days
- description
- The percentage of patients who were alive at 60 days after transfusion.
- measure
- Survial Rate at 100 Days
- timeFrame
- 100 days
- description
- The percentage of patients who were alive at 100 days after transfusion.
- measure
- Survial Rate at 5 Years
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * previously untreated patients with a diagnosis of acute leukemia between the ages of 0 and 50 (AML) and 18 and 50 (ALL) Exclusion Criteria: * all other patients
References
Publications (1)
- BACKGROUNDBlumberg N, Heal JM, Rowe JM. A randomized trial of washed red blood cell and platelet transfusions in adult acute leukemia [ISRCTN76536440]. BMC Blood Disord. 2004 Dec 10;4(1):6. doi: 10.1186/1471-2326-4-6. PMID 15588315