Clinical trial · Interventional
Brief Title : Optimized Endoscopic Submucosal Dissection With Snaring for Colorectal Neoplasm
Comparison of Coventional Endoscopic Submucosal Dissection and Optimized Endoscopic Submucosal Dissection With Snaring for Colorectal Neoplasm
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is aimed to analyze the outcomes after conventional endoscopic submucosal dissection (ESD) and optimized ESD with snaring (oESD-S) for colorectal neoplasm that is more than 20 mm in diameter of laterllay spreading tumor or flat elevated lesion without stalk. Optimized ESD with snaring means submucosal dissection followed by snaring when narrowed circumference of the remained submucosal tissue beneath the lesion is less than 5 mm in diameter with snaring, then resected by using an electric current. The investigators expect optimized ESD with snaring can provide more time-saving procedure with comparable en-bloc resection rate and perforation rate, when compared with the conventional ESD method.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional ESD | Procedure | — | UNRESOLVED |
| Optimized ESD with snaring | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- conventional ESD
- description
- Conventional ESD arm indicates the group in which conventional ESD method is applied for the dissection of colorectal neoplasm.
- interventionNames
- Procedure: Conventional ESD
- type
- EXPERIMENTAL
- label
- Optimized ESD with snaring
- description
- Optimized ESD with snaring arm indicates the group in which optimized ESD with snaring method is applied for the dissection of colorectal neoplasm.
- interventionNames
- Procedure: Optimized ESD with snaring
Primary outcomes (2)
- measure
- procedure time
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * colorectal laterally spreading tumor that is more than 20 mm in diameter * other elevated or flat colorectal neoplasm without stalk, that is more than 20 mm in diameter Exclusion Criteria: * colorectal neoplasms that are proven or suspected to be invaded more than submucosal invasion * colorectal neoplasms that have severe fibrosis beneath the target lesion * patient's refusal to participate this study * less than 18 years old * subjects who cannot consent voluntarily due to the communication difficulty
References
Publications (1)
- DERIVEDBae JH, Yang DH, Lee S, Soh JS, Lee S, Lee HS, Lee HJ, Park SH, Kim KJ, Ye BD, Myung SJ, Yang SK, Byeon JS. Optimized hybrid endoscopic submucosal dissection for colorectal tumors: a randomized controlled trial. Gastrointest Endosc. 2016 Mar;83(3):584-92. doi: 10.1016/j.gie.2015.06.057. Epub 2015 Aug 28. PMID 26320696