Clinical trial · Interventional
Magnesium and Rotational Thromboelastometry (ROTEM) in Colorectal Cancer Surgery
NCT01938300CI-TRIAL-00019894completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Magnesium sulphate is given to the patients during the colorectal cancer surgery under the hypothesis that it would attenuate the postoperative hypercoagulability. The investigators intend to characterize the changes of coagulation in colorectal cancer patients by using the point-of-care device after the infusion of magnesium sulphate.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Magnesium Sulfate | Drug | — | UNRESOLVED |
| Normal saline | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Magnesium
- description
- Magnesium sulfate infusion during a operation period. Infusion regimen: 1. Bolus 50 mg/kg of magnesium sulfate in 100 ml normal saline over 15 minutes 2. Infusion 15 mg/kg/h of magnesium sulfate throughout the operation
- interventionNames
- Drug: Magnesium Sulfate
- type
- PLACEBO_COMPARATOR
- label
- Control
- description
- administration of normal saline as a same volume of magnesium sulphate as a same method.
- interventionNames
- Drug: Normal saline
Primary outcomes (9)
- measure
- Change of maximum clot firmness (MCF) of FIBTEM
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * The patients undergoing a laparoscopic colorectal cancer surgery Exclusion Criteria: * Renal disease * Hepatic disease * Neuromuscular disease * Coagulation disorder * Cardiopulmonary disease
References
Publications (0)
Data not yet available
No reference posted for this study.