Clinical trial · Observational
Biologic Predictors of Leiomyoma Treatment Outcomes
NCT01936493CI-TRIAL-00026635completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to search for the hereditary (genetic) causes of uterine fibroids. Some women with uterine fibroids may have one or more genes that make them more likely to develop uterine fibroids. We are trying to identify these genes to better understand how and why uterine fibroids develop and to design better treatment options for women with uterine fibroids. This information may also help us to understand and treat other problems that may be caused by these genes.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Fibroids | Leiomyoma | ALIAS | 0.90 |
| Myomas | Myoma | ALIAS | 0.90 |
| Uterine Fibroids | Uterine Corpus Leiomyoma | ALIAS | 0.90 |
| Uterine Leiomyomas | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DNA analysis | Genetic | — | UNRESOLVED |
| Hormonal analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Females with uterine fibroids
- description
- Participants will be females age of 18 or older who have be diagnosed with uterine leiomyoma. Study Subjects will be asked if mothers or siblings also have diagnosis of uterine leoimyoma (either past or present diagnosis) and these family members will be invited to participate in this trial. All participants will provide blood samples for serum aliquots for hormonal analysis and genomic DNA analysis, and will answer a baseline genetic epidemiology questionnaire.
- interventionNames
- Genetic: DNA analysis
- Other: Hormonal analysis
Primary outcomes (1)
- measure
- Analyze environmental exposures and genetic predisposition among women exhibiting disease manifestations of uterine fibroids.
- timeFrame
- baseline
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: 1. Able and willing to give consent 2. Age 18 or older 3. Presence of known uterine leiomyoma Exclusion Criteria: 1\. Suspected malignancy
References
Publications (0)
Data not yet available
No reference posted for this study.