Clinical trial · Interventional
Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial
BENEFIT: Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial
NCT01929122CI-TRIAL-00028706BENEFITcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to explore the effects of cooked navy bean powder or rice bran consumption on the stool microbiome and metabolome of colorectal cancer survivors and healthy adults.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer Control and Prevention | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cooked Navy Bean Powder Meals and Snacks | Dietary Supplement | — | UNRESOLVED |
| Placebo-Control Meals and Snacks | Dietary Supplement | — | UNRESOLVED |
| Rice Bran Meals and Snacks | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- PLACEBO_COMPARATOR
- label
- Placebo-Control
- description
- Randomized participants consume 1 meal and 1 snack per day that does not include either rice bran or navy bean powder for 28 days.
- interventionNames
- Dietary Supplement: Placebo-Control Meals and Snacks
- type
- EXPERIMENTAL
- label
- Cooked Navy Bean Powder
- description
- Randomized participants consume 1 meal and 1 snack per day containing cooked navy bean powder (35 g/day) for 28 days.
- interventionNames
- Dietary Supplement: Cooked Navy Bean Powder Meals and Snacks
- type
- EXPERIMENTAL
- label
- Rice Bran
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * ≥ 18 years of age. * Be a Colorectal Cancer Survivor that is a minimum of 4 months post chemotherapy/radiation treatment. OR be a healthy adult with no prior history of treatment for cancer. * BMI between 25-35 * no previous or concurrent malignancy except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer and other cancer for which the patient has been disease free for five years. * Ability to complete questionnaire(s) and dietary food logs * Willingness to consume meals/snacks provided for 28 consecutive days * Drink less than or equal to one alcoholic drink/day Exclusion Criteria: * History of food allergies and/or major dietary restrictions * Pregnant or lactating or planning to become pregnant * Self identified as a smoker * Taking prescribed medication to control their lipids * Taking Bean-O, other anti-flatulence medications or prolonged antibiotic use (one month) * Have a history of gallstones.
References
Publications (3)
- RESULTBorresen EC, Gundlach KA, Wdowik M, Rao S, Brown RJ, Ryan EP. Feasibility of Increased Navy Bean Powder Consumption for Primary and Secondary Colorectal Cancer Prevention. Curr Nutr Food Sci. 2014 May;10(2):112-119. doi: 10.2174/1573401310666140306005934. PMID 25009453
- RESULTBorresen EC, Brown DG, Harbison G, Taylor L, Fairbanks A, O'Malia J, Bazan M, Rao S, Bailey SM, Wdowik M, Weir TL, Brown RJ, Ryan EP. A Randomized Controlled Trial to Increase Navy Bean or Rice Bran Consumption in Colorectal Cancer Survivors. Nutr Cancer. 2016 Nov-Dec;68(8):1269-1280. doi: 10.1080/01635581.2016.1224370. Epub 2016 Sep 30. PMID 27689688
- RESULTSheflin AM, Borresen EC, Kirkwood JS, Boot CM, Whitney AK, Lu S, Brown RJ, Broeckling CD, Ryan EP, Weir TL. Dietary supplementation with rice bran or navy bean alters gut bacterial metabolism in colorectal cancer survivors. Mol Nutr Food Res. 2017 Jan;61(1):10.1002/mnfr.201500905. doi: 10.1002/mnfr.201500905. Epub 2016 Sep 12. PMID 27461523