Clinical trial · Observational
Thromboelastography During Surgery for Malignant Pleural Mesothelioma
NCT01912547CI-TRIAL-00016748unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Surgery for malignant pleural mesothelioma is complex and prolonged, and may involve significant blood loss with considerable blood and product transfusion. Thromboelastography (TEG) is a global assay of coagulation that uses whole blood to produce a tracing that records kinetic changes in clot formation. This study aims provide a better understanding of the coagulation profile of these patients, and will form the basis of a TEG-based transfusion algorithm for future surgeries for mesothelioma.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Coagulopathy | — | UNRESOLVED | — |
| Mesothelioma | Malignant Mesothelioma | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood draw for TEG analysis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Blood draw for TEG analysis
- description
- TEG analysis of blood from patients at different points in time
- interventionNames
- Procedure: Blood draw for TEG analysis
Primary outcomes (1)
- measure
- Coagulation profile during extrapleural pneumonectomy or pleurectomy
- timeFrame
- Surgical period (4-6 hours)
- description
- Reaction time, alpha angle, maximum amplitude and clot lysis from thromboelastography give a better picture of coagulation at different phases of surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult male or female patients undergoing elective surgery for malignant pleural mesothelioma Exclusion Criteria: * Unwilling or unable to provide consent * History of bleeding disorder * On medications that may affect hemostasis
References
Publications (0)
Data not yet available
No reference posted for this study.