Clinical trial · Observational
Detection of Early Esophageal Squamous Neoplasia
Detection of Early Esophageal Squamous Neoplasia by Using Virtual Chromoendoscopy and Probe-based Confocal Laser Endomicroscopy
NCT01909518CI-TRIAL-00011489unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the present study： 1. To investigate the diagnosing value of pCLE for early esophageal squamous neoplasia. 2. To assess the detection rate of early esophageal squamous neoplasia by virtual chromoendoscopy
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Squamous Intraepithelial Neoplasia | Esophageal Squamous Intraepithelial Neoplasia | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- pCLE examination
- description
- pCLE is used to distinguish the suspected lesions detected by I-SCAN in esophagus
Primary outcomes (1)
- measure
- The diagnostic accuracy of pCLE on early esophageal squamous neoplasia
- timeFrame
- 6 month
- description
- Patients will be prospectively recruited to evaluate the diagnostic sensitivity, specificity and accuracy of early esophageal squamous neoplasia by using probe-based confocal laser endomicroscopy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged between 50 and 80 years old * Patients undergo screening endoscopy or histologically verified esophageal squamous intraepithelial neoplasia before. Exclusion Criteria: * Advanced esophageal, gastric or duodenal cancer * History of upper GI tract surgery * Coagulopathy or acute GI bleeding * Pregnant or breast-feeding (for females) * Impaired renal function * Allergy to fluorescein sodium * Inability to provide informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.