Clinical trial · Observational
Markers of Prognosis and Response to Therapy in Patients With Metastatic Brain Tumors Undergoing Stereotactic Radiosurgery (SRS)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This registry study will evaluate patients with metastatic brain tumors undergoing, or having undergone, stereotactic radiosurgery (SRS) at Swedish Medical Center. Clinical outcomes will be evaluated at the 3, 6 and 12-month time points. Clinical data, SRS treatment data, and imaging data (including anatomic and advanced imaging sequences obtained prior to and serially following SRS) will be archived in an online informatics platform, specifically a metastatic brain tumor registry known as the Comprehensive Neuro-oncology Data Repository for Metastatic Tumors (CONDR - Mets).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Brain Tumor | Brain Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Quantitative measures of overall tumor volume will be performed for each subject at the time of SRS
- timeFrame
- At the time of SRS
- measure
- Quantitative measures of tumor number will be performed for each subject at the time of SRS
- timeFrame
- At the time of SRS
- measure
- Overall survival will be measured for each subject (in weeks from SRS to death)
- timeFrame
- Post-SRS
Secondary outcomes (3)
- measure
- Measures of ADC, rCBV, MTT and ktrans will be performed for each treated tumor at treatment and at 6 months following SRS
- timeFrame
- 6 months post SRS
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients (\>18 yo) with a pathological diagnosis of metastatic brain cancer * Participants must have \>4 tumors felt to require stereotactic radiosurgery * Karnofsky scale of \> 70 at the time of initial treatment * Age \< 80 Exclusion Criteria: * Karnofsky scale \<70 * Age \> 80 * Inability to undergo MR imaging studies
References
Publications (0)
Data not yet available