Clinical trial · Observational
Breast Cancer Long-term Outcome of Cardiac Dysfunction
Study of the Cardiovascular and Psychosocial Effects of the Treatment of Breast Cancer With Chemotherapy and/or Radiotherapy
NCT01904331CI-TRIAL-00033324BLOCcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess the prevalence of cardiac dysfunction and (undiagnosed) heart failure in women registered in general practice with a history of breast cancer who received chemotherapy and / or radiotherapy as compared to a matched female control population.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Breast cancer patients
- description
- Women who were curatively treated with chemo- and/or radiotherapy for breast cancer
- label
- Controls
- description
- Women matched on age and general practitioner with the breast cancer patients
Primary outcomes (1)
- measure
- Cardiac dysfunction
- timeFrame
- on average 11 years after treatment with breast cancer
- description
- systolic and diastolic parameters at time of inclusion
Secondary outcomes (1)
- measure
- Biomarkers +DNA
- timeFrame
- on average 11 years after treatment with breast cancer
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * For breast cancer patients: minimum of 5 years after treatment for breast cancer with chemo- and/or radiotherapy and after 1970 * For breast cancer patients: younger than 80 at the time of diagnosis of breast cancer * willing to sign an informed consent * older than 18 at the time of inclusion Exclusion Criteria: * Treatment with chemo- and/or radiotherapy for other types of cancer besides breast cancer * women who are unable to participate (e.g. terminally or mentally ill)
References
Publications (0)
Data not yet available
No reference posted for this study.