Clinical trial · Interventional
Acupoint Electric Stimulation Combined With Tropisetron in Preventing and Treating Nausea and Vomiting After TACE
NCT01895010CI-TRIAL-00011266unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Observation on acupoint electric stimulation combined with tropisetron in preventing and treating nausea and vomiting and improving the patient's appetite after TACE for primary or metastatic liver cancer patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Liver Cancer | Malignant Liver Neoplasm | CURATED_BROADER | 0.78 |
| Nausea | — | UNRESOLVED | — |
| Vomiting | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| acupoint electric stimulation | Device | — | UNRESOLVED |
| tropisetron | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Acupoint and tropisetron
- description
- acupoint electric stimulation combined with tropisetron 6mg before TACE
- interventionNames
- Device: acupoint electric stimulation
- type
- ACTIVE_COMPARATOR
- label
- tropisetron
- description
- treated with tropisetron 6mg before TACE
- interventionNames
- Drug: tropisetron
Primary outcomes (1)
- measure
- Classification of nausea and vomiting
- timeFrame
- 12 month
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * ECOG physical status 0,1,2 * would accept the transcatheter hepatic arterial chemoembolization of primary or metastatic liver cancer patients; * Adult male and female 3, age 18 years old; * the chem-scheme of arterial infusion chemotherapy based on oxaliplatin dosage of 200mg; * signed the informed consent and understand the study design; * Organ function examination in patients must meet the following laboratory indexes: Neutrophil\>500/Ul, hemoglobin \> 8 gm/dL, platelet \>100000/uL,Creatinine \< 2 mg/dL bilirubin \< 1.5 mg/dL, , alanine aminotransferase \< 3 times the normal value, albumin \>30g/L * understand and complete quality of life scale ; * women of childbearing age urine pregnancy test was negative. Exclusion Criteria: * The combined use of other venous chemotherapy within 5 days after TACE; * skin infection on or near the points; * skin hyperalgesia, unable to withstand electrical stimulation; * other confounding factors may cause nausea and vomiting (such as intestinal obstruction, anorexia, etc.); * heart, cerebrovascular accident history or the history of spinal cord injury; * intestinal obstruction lead to nausea and vomiting * installing pacemaker; * cognitive dysfunction, unable to finish Scale; * currently using acupuncture therapy.
References
Publications (1)
- DERIVEDXie J, Chen LH, Ning ZY, Zhang CY, Chen H, Chen Z, Meng ZQ, Zhu XY. Effect of transcutaneous electrical acupoint stimulation combined with palonosetron on chemotherapy-induced nausea and vomiting: a single-blind, randomized, controlled trial. Chin J Cancer. 2017 Jan 10;36(1):6. doi: 10.1186/s40880-016-0176-1. PMID 28069044