Clinical trial · Interventional
CT in Diagnosing Patients With Lung Cancer
Comparison of Conventional Free Breathing CT, 4D CT, and Integrated Active Breath Hold CT Image Acquisition for Lung Cancer
NCT01888510CI-TRIAL-00022920completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial studies computed tomography (CT) in diagnosing patients with lung cancer. Diagnostic procedures, such as CT, may help find and diagnose lung cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 4-dimensional computed tomography | Procedure | — | UNRESOLVED |
| computed tomography | Procedure | — | UNRESOLVED |
| cone-beam computed tomography | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Diagnostic (imaging studies)
- description
- Patients undergo conventional free breathing CT, 4D CT, ABC CT, ABC CBCT, and free breathing CBCT before undergoing radiation therapy.
- interventionNames
- Procedure: computed tomography
- Procedure: 4-dimensional computed tomography
- Procedure: cone-beam computed tomography
Primary outcomes (1)
- measure
- Amount of inter- and intra-physician contouring variability on 4D CT, ABC CT, free breathing CT, and free breathing and ABC CBCT
- timeFrame
- up to 1 week
- description
- A two sided t-test with 5% level of significance will be used.
Secondary outcomes (2)
- measure
- Magnitude and distribution of target and organ at risk volume variations between the different imaging modalities
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Measurable disease on CT scan * Patients with lung cancer visible on CT who are scheduled to receive external beam radiation treatment will be eligible for this study * Patients must be able to perform ABC procedures Exclusion Criteria: * Patients requiring continuous supplemental oxygen due to the requirement of spirometry during all imaging studies * No vulnerable populations will be enrolled (prisoners, children, pregnant females or institutionalized individuals) * Women of childbearing potential will undergo a pregnancy test
References
Publications (0)
Data not yet available
No reference posted for this study.