Clinical trial · Observational
SLEEP AND OSA ON REPRODUCTIVE FUNCTION IN MEN
EFFECTS OF SLEEP LOSS AND OBSTRUCTIVE SLEEP APNEA SYNDROME ON REPRODUCTIVE FUNCTION IN MEN
NCT01884454CI-TRIAL-00020779PSAR01completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In view of the hormonal changes induced by both sleep deprivation and obstructive sleep apnea syndrome (OSA), and the importance of maintaining these hormones in reproductive processes. The present study aims to evaluate the effects of the OSA or sleep deprivation (total or selective REM sleep for 48h) on reproductive function in adult men with normal body mass index.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Obstructive Sleep Apnea | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sleep deprivation | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- Total sleep deprivation
- description
- Healthy volunteers will be submitted to total sleep deprivation (TSD) for 48 hours.
- interventionNames
- Behavioral: Sleep deprivation
- label
- moderate to severe OSA
- description
- Patients diagnosed with moderate to severe obstructive sleep apnea syndrome (OSA) with normal or overweight body mass index (BMI), will be recruited.
- label
- REM sleep deprivation
- description
- Healthy volunteers will be submitted to selective REM sleep deprivation (REMSD) for 48 hours.
- interventionNames
- Behavioral: Sleep deprivation
- label
- Control
- description
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 25 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * men * There is no discrimination of economic class * Age between 25 and 50 * BMI 30 kg/m2 * No prior neurological, psychiatric or use of psychotropic medication * OSA (moderate and severe apnea hypopnea index \> 15) Exclusion Criteria: * smokers * addiction * Individuals with another sleep disorder * Severe uncontrolled organic disease that might interfere with the conduct of the study, such as cancer, heart disease, digestive disorders, diabetes mellitus, male reproductive system * Presence of moderate or severe depression and psychiatric disorders * Volunteers with previous treatment for OSA
References
Publications (0)
Data not yet available
No reference posted for this study.