Clinical trial · Observational
Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging
NCT01884194CI-TRIAL-00020363completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
MRI is useful for diagnosing pinealoblastoma in retinoblastoma patients
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pineoblastoma | Pineoblastoma | ONTOLOGY_EXACT | 0.98 |
| Retinoblastoma | Retinoblastoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Retinoblastoma patients
- description
- patients with diagnosed retinoblastoma
- label
- non-retinoblastoma patients
- description
- aged matched control cohort without the diagnosis of ocular or brain tumor
Primary outcomes (1)
- measure
- Malignancy criteria of pineal gland
- timeFrame
- clinical follow-up 1-year after baseline imaging
- description
- size of pineal gland solid or cystic component (all at baseline)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Day
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosis of retinoblastoma * brain MRI available Exclusion Criteria: * insufficient quality of brain MRI
References
Publications (1)
- DERIVEDPham TT, Siebert E, Asbach P, Willerding G, Erb-Eigner K. Magnetic resonance imaging based morphologic evaluation of the pineal gland for suspected pineoblastoma in retinoblastoma patients and age-matched controls. J Neurol Sci. 2015 Dec 15;359(1-2):185-92. doi: 10.1016/j.jns.2015.10.046. Epub 2015 Oct 28. PMID 26671110