Clinical trial · Interventional
Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Assessment of Cognitive Function After Surgery in Two Types of Anesthesia (General Anesthesia Hypnosedation or Traditional) in Patients Operated for Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The emergence of cognitive disorders after surgery under general anesthesia (GA) is the second leading cause of patient complaints (after dental debris caused by intubation techniques). These cognitive disorders can range from simple reversible confusion (26%) with postoperative cognitive dysfunction without actual recovery (10%). The hypnosedation is an ancient technique of anesthesia expanding its effects on cognitive function remain to this day unknown, but appear promising.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Patients With Breast Cancer and Breast Surgery Requiring | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| general anesthésia | Other | — | UNRESOLVED |
| hypnosedation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- hypnosedation
- description
- hypnosedation
- interventionNames
- Other: hypnosedation
- type
- OTHER
- label
- general anesthesia
- description
- general anesthesia
- interventionNames
- Other: general anesthésia
Primary outcomes (1)
- measure
- Presence of Cognitive Impairment
- timeFrame
- on the 7th day following surgery
- description
- Cognitive impairment is assessed using the MMSE questionnaire (MINI-MENTAL STATE EXAMINATION). the MMSE total score ranges from 0 (alteration of cognition) to 30 (no alteration)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female, over 18 and under 80 years * Diagnosis of breast cancer established (Pathology) * Life expectancy greater than 6 months * Surgery of breast lumpectomy with or without lymph node dissection, mastectomy with or without lymph node dissection, dissection isolated * ASA 1 (healthy patient) or 2 (patient with moderate to high function) according to the classification of the American Society of Anesthesiologist, * Affiliation to a social security scheme, * Information on the study, signed informed consent Exclusion Criteria: * Presence of major psychiatric disorders or psychotic behavior addiction, evaluated by neuropsychologist at the first preoperative consultation, through the test MINI (MINI\> 4 positive responses for each module) * Presence of neurological disorders known untreated or evaluated by neuropsychologist at the first preoperative consultation, with the MMSE test (MMSE \<24) * Patient treated morphine orally for 3 months or more * Patient is pregnant or nursing, or of childbearing potential and not using adequate contraception, * Patient included in another clinical study * Inability to undergo medical monitoring study for geographical, social or psychological * Patient deprived of liberty and most subject to a measure of legal protection or unable to consent
References
Publications (0)
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