Clinical trial · Interventional
Comparison of Analgesic Efficacy and Occurrence of Emesis Among Different Background Infusion and Bolus Administration Regimens of Fentanyl Based Intravenous Patient-controlled Analgesia in Patients After Laparoscopic Assisted Gastrectomy - a Randomized Blind Study -
NCT01863355CI-TRIAL-00010415unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Fentanyl based intravenous patient controlled analgesia(PCA)is popular method for postoperative pain control, but information regarding optimal dose of fentanyl in IV PCA is currently lacking. We thus determine appropriate dose of fentanyl (bolus dose and background infusion rate) for effective pain control with minimal side effects such as nausea and vomiting
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| The Patients With Gastric Cancer Who Are Scheduled to Receive Laparoscopy Assisted Gastrectomy | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| B0 group: bolus 0.6mcg/kg without background infusion | Drug | — | UNRESOLVED |
| BH group: bolus 0.2mcg/kg with background infusion rate 0.4mcg/kg/hr | Drug | — | UNRESOLVED |
| BL group: bolus 0.4mcg/kg with background infusion rate 0.2mcg/kg/hr | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- B0
- description
- (basal rate 0cc/hr, bolus 3cc, lockout time 10min)
- interventionNames
- Drug: B0 group: bolus 0.6mcg/kg without background infusion
- type
- ACTIVE_COMPARATOR
- label
- BL
- description
- (basal rate 1cc/hr, bolus 2cc, lockout time 10min)
- interventionNames
- Drug: BL group: bolus 0.4mcg/kg with background infusion rate 0.2mcg/kg/hr
- type
- ACTIVE_COMPARATOR
- label
- BH
- description
- (basal rate 2cc/hr, bolus 1cc, lockout time 10min)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Age between 20 and 70 * ASA class I and II * Gastric cancer patients who are scheduled to receive laparoscopic gastrectomy Exclusion Criteria: * Cardiovascular disease(uncontrolled hypertension, unstable angina, congestive heart failure, etc.) * Renal failure * Liver failure * Chronic drug or alcohol abuser * Anti-cancer chemotherapy * Chronic opioid use * Use of antiemetics within 24hrs for nausea and vomiting
References
Publications (0)
Data not yet available
No reference posted for this study.