Clinical trial · Observational
Incidence of Postoperative Ketosis and Metabolic Acidosis
NCT01860001CI-TRIAL-00010379POKACIDunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to define the incidence and nature of acidosis after major surgery using Figge's equations to directly measure acidosis. This study will also aim to compare the ability of indirect measures (base deficit, anion gap,corrected anion gap and lactate) to identify the presence of tissue acids in this population. The incidence of postoperative ketoacidosis as a contributor to tissue acidosis will be assessed through the use of point of care urinalysis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metabolic Acidosis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Incidence of tissue acidosis, defined as tissue acids > 5mEq/L (Figge's equation) within one hour of completion of surgery
- timeFrame
- 31/08/13
Secondary outcomes (1)
- measure
- Incidence of metabolic acidosis, defined by base deficit . 2 mEq/L (Henderson-Hasselback) within one hour of completion of surgery.
- timeFrame
- 31/08/13
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who have undergone major cancer surgery * Patients who have an arterial line in place * Patients who have a urinary catheter in place * Patients who will be admitted to intensive care following surgery * Adults \>18 years * Adults who are capable of reading and understanding English Exclusion Criteria: * Patient refusal * Patients without an arterial line or urinary catheter in place * Patients receiving glucose / sliding scale insulin for management of diabetes mellitus
References
Publications (0)
Data not yet available
No reference posted for this study.