Predictive Value of the Distress Thermometer as a Predictive Screening Instrument to Detect Cancer-related Cognitive Impairment in Cancer Patients

Inclusion Criteria:

* Patients should have reached a minimum age of 18 years at the time of enrolment
* Newly detected histologically confirmed diagnosis of a solid (lung, gastro-intestinal, GIST, urological, prostate, breast, sarcoma or gynecological cancer) or hematologic malignancy
* Patients should receive a treatment with curative intent based on the investigator's judgment or have an expected median overall survival of at least 5 years
* Patients scheduled to receive (adjuvant) radiotherapy, chemotherapy, radiobiotherapy, radiochemotherapy, anti-hormonal or targeted therapy with curative intent
* Patients should be able to adequately communicate in Dutch
* Patients should present with a sufficient mental and physical functional status (according to investigator's judgment and first baseline assessment) for completing the questionnaires and neuropsychological assessment

Exclusion Criteria:

* Patients younger than 18 at the time of enrollment
* Patients who present with a cognitive impairment
* Patient receiving a treatment with palliative intent
* Patients who had surgery in the three weeks preceding the baseline assessment
* Patients diagnosed with primary or secondary brain tumors
* Patients with a prior history of cancer during the last 5 years, with or without chemotherapy or radiotherapy
* Patients suffering from organic brain disease
* Patients with an untreated or unstable major medical condition
* Patients who are alcohol or drug dependent
* Patients showing signs of mental deterioration
* Patients with dementia (DSM-IV criteria)
* Patients with a major psychiatric or neurologic disorder that could potentially invalidate assessment; a prior or current diagnosis of a depressive or anxiety disorder is allowed
* Patients presenting with a condition other than cancer in which fatigue is a prominent symptom (such as chronic fatigue symptom)