Clinical trial · Interventional
Postoperative Oral Nutritional Supplementation After Major Gastrointestinal Surgery
Multicenter, Prospective Randomized Controlled Trial Evaluating Postoperative Oral Nutritional Supplementation for the Patients Who Received Major Gastrointestinal Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients who underwent major gastrointestinal surgery is potentially at risk of malnutrition due to reduced oral intake, increased nutritional need, reduced gastrointestinal absorption function, and/or metabolic changes after surgery. The postoperative malnutrition is associated with low quality of life and seems to be related long-term nutritional status. This study is a multicenter, open-labeled prospective randomized clinical trial to examine the effect of postoperative oral nutritional supplements (ONS) after major gastrointestinal surgery by comparing the change of body weight and other nutritional parameters between the experiment group that is supplied with ONS and the control group without ONS.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Biliary Cancer | — | UNRESOLVED | — |
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Duodenal Cancer | Malignant Duodenal Neoplasm | ALIAS | 0.90 |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Inflammatory Bowel Diseases | — | UNRESOLVED | — |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Peptic Ulcer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| oral nutritional supplement | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- ONS group
- description
- oral administration of Encover 2 package for day starting at the time of discharge (200ml/package x 2, total 400Kcal/day) total 87 patients
- interventionNames
- Dietary Supplement: oral nutritional supplement
- type
- NO_INTERVENTION
- label
- Control group
- description
- no intervention total 87 patients
Primary outcomes (1)
- measure
- Body weight decrease rate 8weeks after discharge compared with preoperative body weight
- timeFrame
- 8weeks after discharge
Secondary outcomes (8)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Male or female who are 20 or more years old and not more than 80 years old * Discharge from a hospital is planned within 2 weeks after major gastrointestinal surgery (except when ileostomy is performed) * oral intake is possible at the time of discharge * no preoperative chemotherapy or preoperative radiotherapy * voluntarily agreed with the informed consent of this clinical trial Exclusion Criteria: * Intravenous or other specific nutritional treatment is needed * BMI \>25 and postoperative weight loss is not \> 5% of preoperative body weight at the time of discharge * Allergy to milk, whey, bean, salmon, or the investigational product * Residual of cancer in the abdominal cavity postoperatively if it is cancer case * Presence of synchronous other cancers that needs treatment. * When investigator judged that the patient is not eligible to the trial
References
Publications (0)
Data not yet available