Clinical trial · Interventional
The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer
A Randomized Controlled Trial of the Effectiveness of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer
NCT01833650CI-TRIAL-00119605completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether the use of honey mouthwashes in the prevention of salivary side effects of 131I (radioiodine) therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| thymus honey mouthwash | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- NO_INTERVENTION
- label
- Standard care
- description
- This arm represents the current standard care in patients with thyroid cancer undergoing radioiodine.
- type
- EXPERIMENTAL
- label
- Candy plus thymus honey mouthwash 12
- description
- This arm will consist 30 patients and will be the one of the intervention groups where each patient will be instructed to suck 1 or 2 lemon candies every 2-3 h in the daytime plus 4 thymus honey mouthwashes in between (at least one hour after the candy sucking) starting 12 hours after the ingestion of 131I therapy and for a duration of no more than 4 days.
- interventionNames
- Dietary Supplement: thymus honey mouthwash
- type
- EXPERIMENTAL
- label
- Candy plus thymus honey mouthwash 24
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * \>18 years old * They had a histological diagnosis of papillary, follicular, medullary or anaplastic thyroid cancer * They had undergone total thyroidectomy * They were able to provide consent Exclusion Criteria: * patients who had distant metastases, * a history of salivary-gland disorders, * collagen tissue disease * diabetes mellitus, * previous radioiodine therapy or external radiation to the head or neck * allergy to the honey
References
Publications (0)
Data not yet available
No reference posted for this study.