Clinical trial · Observational
Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas
Observational - Tissue Factor Expression in Bone Sarcomas
NCT01807052CI-TRIAL-00022313completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial studies biomarker expression in tissue samples from patients with bone sarcomas. Studying biomarker in tissue samples from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Localized Osteosarcoma | Osteosarcoma | CURATED_BROADER | 0.78 |
| Metastatic Osteosarcoma | Osteosarcoma | CURATED_BROADER | 0.78 |
| Recurrent Osteosarcoma | Osteosarcoma | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laboratory biomarker analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational
- description
- Tissue samples are analyzed for tumor factor expression levels by immunohistochemistry.
- interventionNames
- Other: laboratory biomarker analysis
Primary outcomes (1)
- measure
- Prevalence of high TF expression
- timeFrame
- 1 month
- description
- Estimated in the analytic population as the number of samples in the population in which such expression is noted divided by 33. An assessment of the precision of such estimates will be provided by an exact binomial confidence interval. Comparison of normalized TF expression in non-metastatic versus metastatic patients will be done using the two-sample t-test.
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria: * Tissue samples from patients with osteosarcomas obtained from the CHTN: * P9754 clinical trial for patients with non-metastatic osteosarcoma * AOST0121 clinical trial for patients with metastatic or recurrent osteosarcoma
References
Publications (0)
Data not yet available
No reference posted for this study.