Clinical trial · Interventional
Intravenous Artesunate and Malaria
Intravenous Artesunate Versus Quinine in Severe Malaria at Kassla, Sudan
NCT01805232CI-TRIAL-00009653IVASunknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Intravenous artesunate is egual to quinine in the treatment of severe malaria
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malaria | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| artesunate | Drug | — | UNRESOLVED |
| Quinine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- artesunate
- description
- intravenous artesunate 80 mg/kg initially then after 8 hours then daily
- interventionNames
- Drug: artesunate
- Drug: Quinine
- type
- ACTIVE_COMPARATOR
- label
- quinine
- description
- quinine infusion 80 mg/kg every 8 hours
- interventionNames
- Drug: artesunate
- Drug: Quinine
Primary outcomes (1)
- measure
- clearance of the parasite and fever
- timeFrame
- 3 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: severe P.falciparum malaria- Exclusion Criteria: mixed infection Pregnant women -
References
Publications (1)
- BACKGROUNDEltahir HG, Omer AA, Mohamed AA, Adam I. Comparison of artesunate and quinine in the treatment of Sudanese children with severe Plasmodium falciparum malaria. Trans R Soc Trop Med Hyg. 2010 Oct;104(10):684-6. doi: 10.1016/j.trstmh.2010.05.009. Epub 2010 Jun 17. PMID 20850004