Clinical trial · Observational
Prevalence and Incidence of Central Airway Obstruction in Advanced Lung Cancer
Prevalence, Incidence and Predictors of Central Airway Obstruction in Patients With Advanced Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Staff constraints made it impossibile to enroll consecutive patients, making the sample not representative of the true cancer population
Summary
Brief summary (as posted)
Lung cancer may cause central airway obstruction through several different mechanisms (invasion by the primary tumor, invasion by metastatic lymph nodes, airway metastasis). The aim of the present study is to determine the prevalence at the time of diagnosis, the incidence at 1 year from the diagnosis, and the predictors of central airway obstruction associated with advanced lung cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Lung Cancer
- description
- All patients with advanced lung cancer candidate for chemotherapy or chemotherapy + radiation therapy will be enrolled and followed-up for 1 year clinically and radiologically (Chest CT) to verify whether or not central airway obstruction is present at the time of diagnosis or occurs in the year following diagnosis (or in the life span from diagnosis and death in patients who die before 1 year of diagnosis). Furthermore, predictor variables possibly associated with central airway obstruction will be studied.
Primary outcomes (1)
- measure
- Incidence of central airway obstruction
- timeFrame
- 12 months
- description
- The incidence will be measured over a 12 month period after diagnosis (or over the life span from diagnosis to death in patients who die before 1 year from the diagnosis)
Secondary outcomes (2)
- measure
- Predictor variables associated with the presence/occurrence of central airway obstruction
- timeFrame
- 12 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Advanced lung cancer with indication for chemotherapy or chemotherapy + radiation therapy Exclusion Criteria: * Age \< 18 year * Pregnancy * Refusal to sign informed consent
References
Publications (0)
Data not yet available