Clinical trial · Interventional
Oral Iohexol for Fecal/Fluid Tagging for CT Colonography: A Study to Improve Image Quality by Preventing Colonic Bubbles
NCT01790139CI-TRIAL-00014095completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To determine whether colonic bubbles associated with CT colonography performed with iohexol for fecal/fluid tagging could be reduced by adding simethicone to the standard cathartic preparation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Oral simethicone | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control
- description
- Control group undergoes CT colonography after usual cathartic bowel cleansing using Colonlyte and fecal/fluid tagging. The tagging is done by administering orally 50 mL of iohexol (Omnipaque 350, GE Healthcare) 10 minutes after the completion of Colonlyte.
- type
- EXPERIMENTAL
- label
- Intervention-Oral Simethicone
- description
- Intervention group undergoes CT colonography after usual cathartic bowel cleansing using Colonlyte, fecal/fluid tagging, and oral administration of simethicone. The tagging is done by administering orally 50 mL of iohexol (Omnipaque 350, GE Healthcare) 10 minutes after the completion of Colonlyte. As the interventional procedure in this intervention group, 10 mL of simethicone is administered orally immediately following the administration of iohexol.
- interventionNames
- Drug: Oral simethicone
Primary outcomes (1)
- measure
- Colonic bubble-related image quality
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients who are schedule to undergo colonoscopy for a suspicion of colonic neoplasia at the investigators' institution * Those who agree to participate in the study Exclusion Criteria: * Colonoscopy for reasons other than detecting colonic neoplasia, e.g. evaluation of inflammatory bowel disease * Contraindications to iodinated contrast including renal insufficiency, hypersensitivity, and hyperthyroidism * Acute severe colonic obstruction which is likely preclude safe and successful performance of CTC * Patient who is suspicious for colonic perforation * Pregnancy * Phenylketonuria (contraindication to simethicone)
References
Publications (0)
Data not yet available
No reference posted for this study.