Clinical trial · Interventional
Gefitinib Versus Pemetrexed for Previously Treated NSCLC Patients
Randomized Phase II Study of Pemetrexed Versus Gefitinib in Previously Treated Patients With Advanced Non-small Cell Lung Cancer
NCT01783834CI-TRIAL-00020881completedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To compare the efficacy of gefitinib versus pemetrexed as second-line chemotherapy for patients with previous treated non-small cell lung cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Previous Treated Metastatic Non-small Cell Lung Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gefitinib | Drug | Gefitinib | ALIAS |
| Pemetrexed | Drug | Pemetrexed | ALIAS |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- pemetrexed
- description
- pemetrexed
- interventionNames
- Drug: Pemetrexed
- type
- ACTIVE_COMPARATOR
- label
- gefitinib
- description
- gefitinib
- interventionNames
- Drug: Gefitinib
Primary outcomes (1)
- measure
- Overall response rate
- timeFrame
- 5 years
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Cells pathologically diagnosed as histological or radical surgery or radiation therapy is not possible stage IIIB and stage IV non-small-cell lung cancer patients * second line * ECOG 0～2 * Patients with normal liver function and renal function Exclusion Criteria: * Patients with severe acute infection requiring antibiotic therapy * Patients who have received treatment in other areas of cancer within 5 years * During pregnancy and lactation patients
References
Publications (0)
Data not yet available
No reference posted for this study.