Clinical trial · Interventional
Comparison of Pleural Drainage Systems on Reducing Pleural Effusion Formation Following Lung Resection
Effect of the Use of a Digital Pleural Drainage System on Reducing Pleural Effusion Formation Following Lung Resection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The chest cavity contains a small amount of fluid (pleural effusion). In normal circumstances this fluid is kept in balance. When surgery is performed on the lung, there can be accumulation of more fluid due to many causes. In order to drain this additional amount of pleural fluid, chest tube(s) are left in the thoracic cage after a lung resection procedure. The investigators are attempting to reduce the amount of pleural fluid production and formation by using a more balanced thoracic drainage system, which adjusts the amount of suction depending on the needs of the patient. That way, the amount of inflammation in the thoracic cage might be smaller, and hence less fluid will be formed. By this, the investigators are hoping that the chest tubes can be removed earlier, and the patients can be discharged faster and will potentially have a lower rate of re-admission to the hospital after surgery due to problems related to the fluid in the thoracic cage.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pleural Effusion | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Atrium Express Dry Seal Chest Drain | Device | — | UNRESOLVED |
| Medela Thopaz Thoracic Drainage System | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Digital thoracic drainage system
- description
- Medela Thopaz Thoracic Drainage System
- interventionNames
- Device: Medela Thopaz Thoracic Drainage System
- type
- ACTIVE_COMPARATOR
- label
- Non-digital thoracic drainage system
- description
- Atrium Express Dry Seal Chest Drain
- interventionNames
- Device: Atrium Express Dry Seal Chest Drain
Primary outcomes (1)
- measure
- Overall quantity of pleural effusion (mL)
- timeFrame
- From one hour after surgery to chest tube removal, estimated duration of 3 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Participants must be between 18 and 90 years of age * Diagnosed with suspected lung cancer or metastatic cancer to the lungs * Surgery must include lung resection (Wedge; single or multiple, lobectomy or bi-lobectomy) and mediastinal lymph nodes sampling or dissection * Demonstrate an ability for understanding the study procedures * Demonstrate willingness to remain on-study for the complete duration * Must be able to give informed consent to participate at this study. Exclusion Criteria: * Patients undergoing lung resection due to non-malignancy * Patients undergoing pneumonectomy * Patients treated with neo-adjuvant chemotherapy and/or radiation prior to surgery * Patients with previous lung resection on the ipsilateral side * Patients with evidence of chronic heart failure (i.e. NYHA class III, IV; current treatment with diuretics for heart failure, and/or LVEF \<35%) * Patients with chronic renal failure (i.e. estimated CCr of \< 50ml/min/m2) * Patients with history of or ongoing liver disease, expressed by ascites or previous peritoneal tapping for ascites.
References
Publications (0)
Data not yet available