Clinical trial · Interventional
Training Effects Following Resection Surgery in Patients With Lung Cancer
NCT01771796CI-TRIAL-00020937EMITORcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine the potential benefits resulting from a specific training on exercise tolerance and muscle function at the medium and long-time, as well as study its effects on plasmatic mediators (sMICA, IGF-I and IGFBP-3) in patients with lung cancer following resection surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic and muscle resistance training | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Aerobic and muscle resistance training
- interventionNames
- Behavioral: Aerobic and muscle resistance training
- type
- NO_INTERVENTION
- label
- Usual care group
- description
- All patients (intervention and usual care group) are patients with lung cancer who underwent a resection surgery.
Primary outcomes (1)
- measure
- Peak oxygen uptake (VO2peak) determined by a cardiopulmonary effort test (CPET)
- timeFrame
- 3 times a week during 8 weeks
- description
- VO2peak is determined by a standardised incremental exercise test. Subjects are instructed to pedal in an electrically braked cycloergometer and are encouraged to continue until they are not able to sustain the target frequency (55-65 rpm). Loads are increased by 25 watts every 2 minutes. Different ventilatory, cardiovascular, metabolic and oxygenation variables are monitored throughout the test using a calibrated exercise system, a standard electrocardiograph, an automatic sphygmomanometer and a finger probe connected to the aforementioned digital recorder. Normal values published by Jones et al are used as the reference for physiological parameters, except for the maximum heart rate which was calculated from a standard equation published by Wassermann et al.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * 1\) age under 80 years. * 2\) patients with lung cancer stage I or II with surgery indication. * 3\) ability to understand and accept the trial procedures and to sign an informed consent. Exclusion Criteria: * 1\) Serious cardiovascular, neuromuscular or metabolic conditions that could interfere with the results and/or interfere with the measurements. * 2\) complementary cancer treatment pre-or post-surgery. * 3\) treatment with drugs with potential effect on muscle structure and function (steroids, anabolic steroids, thyroid hormones and immunosuppressive). * 4\) cognitive or language barriers that impede the realization of the objective of the study and / or collaboration in the exercise program.
References
Publications (0)
Data not yet available
No reference posted for this study.