Clinical trial · Observational
Effect of CCRT on Respiratory Performance and Functional Capacity in Esophagus Cancer Patients
Effect of Concurrent Chemoradiation Therapy on Respiratory Muscle Performance, Lung Function and Functional Capacity in Patients With Primary Esophagus Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purposes of this study are to investigate in patients with newly diagnosed esophageal cancer: 1)changes in pulmonary and respiratory muscle function, functional capacity and quality of life during and after RT or CCRT treatment; 2)the correlations between these changes; and 3)the impacts of these changes on the postoperative pulmonary complications following esophagectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| respiratory muscle performance | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- esophagus cancer patients
- description
- Respiratory muscle performance will be followed in patients with esophagus cancer during CCRT or RT treatments.
- interventionNames
- Behavioral: respiratory muscle performance
Primary outcomes (1)
- measure
- Changes of respiratory muscle performance (MIP/MEP, PFT)from baseline
- timeFrame
- Baseline, during CCRT or RT treatment (Day 5, Day 10, Day 15, Day 20, Day 25), 2 weeks after the completion of the treatment, 1 day pre-operation, and 1 month after operation
- description
- Maximum inspiratory pressure (MIP) Maximum expiratory pressure (MEP) PFT: FEV1, FVC, FEV1/FVC
Secondary outcomes (3)
- measure
- Changes of functional exercise capacity, dyspnea, and quality of life from baseline
- timeFrame
- Baseline, during CCRT or RT treatment (Day 5, Day 10, Day 15, Day 20, Day 25), 2 weeks after the completion of the treatment, 1 day pre-operation, and 1 month after operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * primary esophagus cancer * planning to receive radiation therapy Exclusion Criteria: * MMSE \< 24 * A clinical diagnosis affecting respiratory muscle function and functional activity performance * Unstable angina or acute myocardial infarction prior 1 month of assessment
References
Publications (0)
Data not yet available