Clinical trial · Interventional
Study of Hypotensive Hematopoietic Malignancy Patients' USCOM Readings
A Pilot Feasibility Study of Hypotensive Hematopoietic Malignancy Patients' USCOM Readings
NCT01755000CI-TRIAL-00011972completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to test how practical it is to use the Ultrasonic Cardiac Output Monitor (USCOM), an FDA-approved device, on oncology patients (specifically those with blood cancers). Additionally, the researchers will learn if the USCOM gives additional information about patients' conditions when their blood pressures drop and they are treated with intravenous fluids.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukemia | Leukemia | ONTOLOGY_EXACT | 0.90 |
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
| Myelodysplastic Syndromes | Myelodysplastic Syndrome | ALIAS | 0.90 |
| Paraproteinemias | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fluid Bolus | Procedure | — | UNRESOLVED |
| USCOM scan | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- OTHER
- label
- Aim 1: Hemodynamically Healthy Patients
- description
- Nurse 1 will perform an USCOM scan and record values of Vpk and SV on the clinical data sheet. Nurse 2 will perform the USCOM second scan within five minutes of Nurse 1's scan and record the values of Vpk and SV on the clinical data sheet. Nurse 1 and 2 will be blinded to each other's scans by using separate clinical data forms
- interventionNames
- Procedure: USCOM scan
- type
- OTHER
- label
- Aim 2: Hemodynamically Unstable Patients
- description
- Nurse 1 will perform an USCOM scan and record values of Vpk and SV on the clinical data sheet. Nurse 2 will also be notified of the hypotensive event, will then perform the USCOM second scan within five minutes of PI's scan and record the values of Vpk and SV on the clinical data sheet. The two USCOM scans will be completed within 10 minutes of the hypotensive episode. Nurse 1 and Nurse 2 will be blinded to each other's scans by using separate clinical data forms.
- interventionNames
- Procedure: USCOM scan
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: -≥ 18 years of age * English speaker * Diagnosis of blood dyscrasia, hematopoietic malignancy, or condition that may requires HSCT Exclusion Criteria: * Obstruction of the suprasternal notch that prevents placing the USCOM probe in the correct location * Tracheostomy or endotracheal tube that prevents placing USCOM probe in the correct location * Inability to lie flat, on left or right side, or with the head of bed at a 30 degree angle for the USCOM exam (ex. due to respiratory distress or physiologic reasons) * Impairment by a psychiatric, cognitive, or physiologic disorder that limits ability to understand explanation of study and give consent
References
Publications (0)
Data not yet available
No reference posted for this study.