Clinical trial · Interventional
Radiofrequency Ablation in Thyroid Nodules
Efficacy of Radiofrequency Ablation in Thyroid Nodules
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Thyroid nodules are common problems and although \> 95% are stated to be benign, they may cause some problems like hyperthyroidism, compression symptoms, and cosmesis associated with their function, size and localization. Especially for these nodules, patients undergo surgery and face up with the problems associated with surgical complications although they are not cancer. In some studies, radiofrequency ablation previously used for intrabdominal tumors like hepatic metastasis...,was stated to be efficient in the treatment of benign thyroid nodules and in some recurrent thyroid cancer cases. Therefore, the investigators decided to use this method in our patients having nodules like previously mentioned and see the efficacy and safety of the technique.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodules | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Radiofrequency ablation of the thyroid nodule | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- radiofrequency ablation of thyroid nodule
- description
- Under ultrasonography the thyroid nodules will be ablated by radiofrequency ablation
- interventionNames
- Procedure: Radiofrequency ablation of the thyroid nodule
Primary outcomes (1)
- measure
- Shrinkage of the thyroid nodule after radiofrequency ablation
- timeFrame
- 6 months
Secondary outcomes (1)
- measure
- Disappearance of the nodules in follow up
- timeFrame
- 1 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. the presence of subjective symptoms (foreign body sensation, neck discomfort or pain, compressive symptom) or cosmetic problems; 2. a poor surgical candidate or refusal to undergo surgery; 3. fine-needle aspiration cytology and US findings that were compatible with a benign nodule; 4. anxiety about a malignancy. Exclusion Criteria: 1. a nodule less than 5 mm in size; 2. follicular neoplasm or malignancy on fine needle aspiration cytology (FNAC); 3. a nodule with the sonographic criteria for a malignancy (taller than wide, marked hypoechoic, microcalcifications, ill-defined margins), although FNAC was a benign result; 4. previous radiation or operation history to the head and neck; (5) previous sclerosing therapy.
References
Publications (0)
Data not yet available