Clinical trial · Interventional
Microsphere Localization Using PET/MRI or PET/CT in Patients Following Radioembolization
Pilot Study of Microsphere Localization Using PET/MRI or PET/CT in Patients Following Radioembolization
NCT01744054CI-TRIAL-00031917terminatedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Logistics regarding PET/CT portion of study
Summary
Brief summary (as posted)
The successful localization of the y90 microspheres by PET/MR and/or PET/CT scans would be a useful tool in individualizing patient care after the radioembolization procedure. The information from a PET/MR or PET/CT scan would allow for early evaluation of the technical success of the procedure.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Neoplasms | Liver Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PET/CT | Device | — | UNRESOLVED |
| PET/MR | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- PET/MR or PET/CT
- description
- * Patients must have had radioembolization, within 72 hours of the PET/MR or PET/CT * Subjects will be asked to lie still within the scanner for up to 1.5 hours while images are acquired for the liver
- interventionNames
- Device: PET/MR
- Device: PET/CT
Primary outcomes (2)
- measure
- Evaluate y90-PET/MRI and PET/CT for potential on reporting presence of extrahepatic deposition of microspheres
- timeFrame
- 1 day (one time event for patient)
- description
- A diagnostic radiologist and a nuclear medicine physician will evaluate the images and will determine any presence of extrahepatic deposition of microspheres.
- measure
- Evaluate y90-PET/MRI and PET/CT for potential on reporting technical success of radioembolization
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Participant must successfully complete the MRI screening form if receiving an MRI * Participant must be scheduled to undergo radioembolization for any indication * Participant must be ≥ 18 years of age * Participant must be able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent document Exclusion Criteria: * Participant must not have any contraindications to MRI scanning * Patient must not be pregnant or breastfeeding * If agreeing to MRI contrast, participant must not have renal insufficiency (glomerular filtration rate (GFR \< 30 mL/min/1.73 m2) measured within the past 60 days * If agreeing to MRI contrast, participant must not be on dialysis * If agreeing to MRI contrast, participant must not have had a prior allergic reaction to gadolinium-based contrast agents * PET/MRI or PET/CT is not able to be scheduled within 72 hours of radioembolization
References
Publications (0)
Data not yet available
No reference posted for this study.