Clinical trial · Observational
Persistent Pain After Reconstruction Following Mastectomy
NCT01738048CI-TRIAL-00008558completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A cross sectional study to determine the prevalence of persistent pain after reconstructive surgery after mastectomy for breast cancer, with a comparative analysis of a cohort treated with mastectomy without reconstruction.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Chronic Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Mastectomy
- description
- Patients treated with mastectomy without reconstruction
- label
- Reconstruction
- description
- Patients treated with mastectomy followed by reconstruction
- interventionNames
- Procedure: Reconstruction
Primary outcomes (1)
- measure
- The risk of developing persistent if reconstructed
- timeFrame
- Cross-sectional, 2-3 years after surgery for breast cancer
- description
- The risk of developing persistent if reconstructed compared to patients mastectomized without reconstruction expressed as an odds ratio.
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with unilateral primary breast cancer aged 18-70 years Exclusion Criteria: * recurrent cancer * other malignancy * emigration * non-standardized treatment
References
Publications (1)
- BACKGROUNDAndersen KG, Kehlet H. Persistent pain after breast cancer treatment: a critical review of risk factors and strategies for prevention. J Pain. 2011 Jul;12(7):725-46. doi: 10.1016/j.jpain.2010.12.005. Epub 2011 Mar 24. PMID 21435953