Clinical trial · Interventional
Pilot Study of Zoledronic Acid in Combination With First-line Chemotherapy in Aged Patients With Lung Cancer
NCT01737216CI-TRIAL-00008759unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pilot study of Zoledronic acid in combination with first-line chemotherapy in aged patients with lung cancer. The purpose is to assess the effects of Zoledronic acid in combination with first-line chemotherapy in aged patients with lung cancer on bone mineral density gain in the lumbar spine and total hip.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EP/TP | Drug | — | UNRESOLVED |
| Zoledronic acid plus EP/TP | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Zoledronic acid plus First-line chemotherapy
- interventionNames
- Drug: Zoledronic acid plus EP/TP
- type
- ACTIVE_COMPARATOR
- label
- First-line chemotherapy
- interventionNames
- Drug: EP/TP
Primary outcomes (1)
- measure
- Progression-free survival(PFS)
- timeFrame
- 1 year
Secondary outcomes (3)
- measure
- Overall survival(OS)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Signed informed consent form * Age ≥70 years * Performance Status- Eastern Cooperative Oncology Group (ECOG) 0-1 * Histologically or cytologically confirmed lung cancer * Did not receive bisphosphonate treatment Exclusion Criteria: * Appear relapse and metastasis * receive other bisphosphonate treatment * Active or uncontrolled infection * Pregnant or lactating women
References
Publications (0)
Data not yet available
No reference posted for this study.