Clinical trial · Interventional
Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
A Prospective Randomized Clinical Trial of Two Surgical Techniques for Pancreaticojejunostomy in Patients Undergoing Pancreaticoduodenectomy: Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pancreaticojejunostomy is the key procedure of pancreaticoduodenectomy. The aim of our study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "nonstented stump-closed pancreaticojejunostomy" in pancreatoduodenectomy, which could provide a feasible option to pancreatic surgeons for patients with pancreaticoduodenectomy.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Biliary Tract Neoplasms | — | UNRESOLVED | — |
| Duodenal Neoplasms | Duodenal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pancreatic Neoplasms | Pancreatic Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pancreatitis, Chronic | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pancreaticojejunostomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Nonstented stump-closed anastomosis
- description
- Nonstented stump-closed anastomosis is used for pancreaticojejunostomy after pancreaticoduodenectomy.
- interventionNames
- Procedure: pancreaticojejunostomy
- type
- ACTIVE_COMPARATOR
- label
- Duct-to-mucosa anastomosis
- description
- Duct-to-mucosa technique is used for pancreaticojejunostomy after pancreaticoduodenectomy.
- interventionNames
- Procedure: pancreaticojejunostomy
Primary outcomes (1)
- measure
- the postoperative pancreatic fistula(POPF) rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Informed consent * 18-80 years old; * Eastern Cooperative Oncology Group(ECOG) 0-2 * Patients must have undergone pancreaticoduodenectomy. * Preoperative enhanced CT scan shows respectable or borderline resectable neoplasm * Without distal metastasis Exclusion Criteria: * Patients who have had previous pancreatic body tail resection rese * immunodeficiency, people infected with HIV * patients with severe cardiopulmonary function, liver and renal function * infection without control or active infections * Pregnant patients.
References
Publications (1)
- DERIVEDXu J, Zhang B, Shi S, Qin Y, Ji S, Xu W, Liu J, Liu L, Liu C, Long J, Ni Q, Yu X. Papillary-like main pancreatic duct invaginated pancreaticojejunostomy versus duct-to-mucosa pancreaticojejunostomy after pancreaticoduodenectomy: A prospective randomized trial. Surgery. 2015 Nov;158(5):1211-8. doi: 10.1016/j.surg.2015.04.020. Epub 2015 May 30. PMID 26036878