Clinical trial · Observational
Optical Detection of Peripheral Nerve Bundles During Surgery
In Vivo Identification of Peripheral Nerve Bundles During Surgery Using Optical Spectroscopy Techniques - a Pilot Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Investigation of application possibilities of optical spectroscopy within the field of surgical resection procedures to spare nerve tissue. Optical spectroscopy enables the possibility to specifically differentiate between different (human) tissues. The hypothesis is that incorporation of this technique into existing medical devices (e.g. medical blade) would enlarge the accuracy and reliability of these devices. Sparing of nerve bundles during surgery can lead to decreased postoperative morbidity rates.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Carcinoma of Parotid Gland | Parotid Gland Carcinoma | ALIAS | 0.90 |
| Colon Rectal Cancer Tubulovillous Adenocarcinoma | — | UNRESOLVED | — |
| Malignant Lymphoma of Lymph Nodes of Axillary | — | UNRESOLVED | — |
| Malignant Lymphoma of Lymph Nodes of Inguinal Region | — | UNRESOLVED | — |
| Malignant Lymphoma of Lymph Nodes of the Cervix | — | UNRESOLVED | — |
| Tumor of Soft Tissue of Head, Face and Neck | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgical resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Surgical resections
- description
- Patients planned for elective inguinal, axillary or cervical lymph node dissection or parotidectomy, patients with rectal cancer undergoing rectal surgery and patients undergoing resection of a soft tissue tumour.
- interventionNames
- Procedure: Surgical resection
Primary outcomes (1)
- measure
- Differentiation between nerve tissue and its surrounding tissue
- timeFrame
- Day 0
- description
- Statistical analysis of the difference between diffuse reflectance spectra obtained at nerve tissue and its surrounding tissue measurement locations
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients planned for elective inguinal, axillary or cervical lymph node dissection or parotidectomy , patients with rectal cancer undergoing rectal surgery and patients undergoing resection of a soft tissue tumour. * Patients that have provided a signed informed consent * Patients ≥ 18 years old Exclusion Criteria: • Patients with suspected sensitivity to light; e.g. patients who have had photodynamic therapy
References
Publications (0)
Data not yet available