Clinical trial · Interventional
Collaborative Targeted Case Management in Improving Functional Status in Patients With Stage III-IV Cancer
MC1193: Collaborative Care to Preserve Performance in Cancer (COPE)
NCT01721343CI-TRIAL-00105561completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized clinical trial studies collaborative targeted case management in improving functional status in patients with stage III-IV cancer. Collaborative targeted case management may improve functional mobility, improve quality of life, and reduce pain and health care utilization in patients with advanced cancer
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cognitive/Functional Effects | — | UNRESOLVED | — |
| Malignant Neoplasm | Malignant Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Pain | — | UNRESOLVED | — |
Interventions
Interventions (8)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| assessment of therapy complications | Procedure | — | UNRESOLVED |
| case management | Other | — | UNRESOLVED |
| educational intervention | Other | — | UNRESOLVED |
| management of therapy complications | Procedure | — | UNRESOLVED |
| physical therapy | Procedure | — | UNRESOLVED |
| quality-of-life assessment | Procedure | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
| telephone-based intervention | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Arm I (enhanced usual care)
- description
- Patients undergo enhanced usual care comprising telephonic monitoring with monthly status reports provided to their oncology care teams for 6 months.
- interventionNames
- Behavioral: telephone-based intervention
- Other: questionnaire administration
- Procedure: quality-of-life assessment
- Procedure: management of therapy complications
- Procedure: assessment of therapy complications
- type
- EXPERIMENTAL
- label
- Arm II (enhanced usual care, RCM)
- description
- Patients undergo enhanced usual care as in Arm I and participate in an individualized conditioning program delivered telephonically by the Fitness Care Manager (FCM) and adapted, as required, by a local physical therapist for 6 months.
- interventionNames
- Behavioral: telephone-based intervention
- Other: case management
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of stage III or stage IV cancer * Life expectancy \> 6 months * Ambulatory Post Acute Care (APC) score between 53 and 66 * Ability to complete questionnaire(s) by themselves or with assistance * Provide informed written consent * Have working phone to communicate with study team * Fluent in English * Sufficient auditory acuity * Intact cognitive status Exclusion Criteria: * Patient is within 2 months of a major surgical procedure
References
Publications (2)
- BACKGROUNDCheville AL, Moynihan T, Basford JR, Nyman JA, Tuma ML, Macken DA, Therneau T, Satelel D, Kroenke K. The rationale, design, and methods of a randomized, controlled trial to evaluate the effectiveness of collaborative telecare in preserving function among patients with late stage cancer and hematologic conditions. Contemp Clin Trials. 2018 Jan;64:254-264. doi: 10.1016/j.cct.2017.08.021. Epub 2017 Sep 5. PMID 28887068
- RESULTCheville AL, Moynihan T, Herrin J, Loprinzi C, Kroenke K. Effect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer: A Randomized Clinical Trial. JAMA Oncol. 2019 May 1;5(5):644-652. doi: 10.1001/jamaoncol.2019.0011. PMID 30946436