Clinical trial · Interventional
17% Salicylate Versus 17% Salicylate-Ethyl Pyruvate for Plantar Foot Warts
New Formulation of Salicylate to Improve Treatment of Common Skin Warts
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Plantar warts on the sole of the foot are among the most common warts seen in podiatry clinics. Some patients are readily cured by simple standard of care treatments that include wart debridement (trimming or excision) and application of 17% salicylate (commercially known as Compound W)or by other treatments that may be painful and affect mobility. No treatment is consistently effective and most patients fail treatment multiple times. Ethyl pyruvate (EP)is a common food additive noted to be 'generally regarded as safe' that may improve the activity of salicylate in wart treatment by improving the ability to penetrate and/or persist in the skin. The use of 17% salicylate with the addition of EP may improve cures of common foot plantar warts in subjects who also be receiving other standard-of-care treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Warts | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 17% Salicylate with ethyl pyruvate | Drug | — | UNRESOLVED |
| Salicylates | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 17% Salicylate with Ethyl Pyruvate
- description
- Subjects with plantar wart(s) will apply the product to warts twice a day for up to 16 weeks.
- interventionNames
- Drug: 17% Salicylate with ethyl pyruvate
- type
- ACTIVE_COMPARATOR
- label
- 17% salicylate
- description
- subjects will apply 17% salicylate (standard of care treatment) to plantar skin wart(s) twice a day for up to 16 weeks
- interventionNames
- Drug: Salicylates
Primary outcomes (1)
- measure
- To determine if salicylate with ethyl pyruvate (SA-EP) eliminates plantar warts more quickly than salicylate (SA) alone.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * evidence of skin plantar wart(s) Exclusion Criteria: * iodine allergy
References
Publications (0)
Data not yet available