Clinical trial · Interventional
Success of Paravertebral Blocks in Analgesia for Interventional Hepatic Procedures
Randomised Double Blind Controlled Study of the Effectiveness of Paravertebral Nerve Block in Decreasing Analgesia Requirements and Improving Patient Experience During Interventional Hepatic Procedures.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Institutional Ethics Board concern regarding sham procedure, requiring modifications that are not feasible within the man-power limitations of our institution.
Summary
Brief summary (as posted)
This study is aimed at assessing whether performing a paravertebral block (a type of regional pain relief) can reduce the pain and anxiety patients experience during radiological procedures on the liver.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Neoplasms | Liver Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Control sham procedure | Procedure | — | UNRESOLVED |
| Paravertebral block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Paravertebral block
- description
- Paravertebral space will be needled and an anesthetic agent will be injected.
- interventionNames
- Procedure: Paravertebral block
- type
- PLACEBO_COMPARATOR
- label
- Control sham procedure
- description
- Paravertebral space will be needled, but only normal saline injected.
- interventionNames
- Procedure: Control sham procedure
Primary outcomes (1)
- measure
- Dose of intravenous sedation required during and after the procedure
- timeFrame
- 1 hour
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 95 Years
Show eligibility criteria text
Inclusion Criteria: * Male or non-pregnant female subjects, between the ages of 18 and 80 at the time of enrollment. Subjects referred for liver/biliary interventions to the angiography department. Written informed consent to participate in the study. Ability to comply with the requirements of the study procedures Exclusion Criteria: * Subjects who participated in an active stage of any drug, intervention or treatment trial within 30 days of enrollment. Subjects with preexisting conditions, which, in the opinion of the investigator, interfere with the conduct of the study. Patients will only be excluded on this basis following discussion with another interventional radiologist. Subjects who are uncooperative or cannot follow instructions. Mental state that may preclude completion of the study procedure or ability to obtain informed consent. Pregnant or nursing female subjects. Patient who are to undergo liver biopsy or routine biliary tube exchange. Patients with neurological/spinal conditions, or a BMI over 40, that would prevent safe/effective or well-targeted paravertebral blockade. Patient unable to tolerate the paravertebral block procedure, for example due to inability to lie prone
References
Publications (0)
Data not yet available