Clinical trial · Interventional
Neoviderm Skin Emulsion in the Prevention of Radiation Dermatitis
A Phase II Study Designed to Evaluate the Value of Neoviderm Skin Emulsion in the Prevention of Radiation Dermatitis for Patients Undergoing External Radiation Therapy
NCT01701466CI-TRIAL-00018017terminatedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether NeoVIDERM is effective at preventing radiation dermatitis in patients receiving external beam radiation therapy to the head and neck or breast areas.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aveeno cream | Other | — | UNRESOLVED |
| Flamazine cream | Other | — | UNRESOLVED |
| NeoVIDERM cream | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm B: standard of care plus NeoVIDERM cream
- description
- Patients will apply NeoVIDERM cream to the treatment area everyday one week before starting radiotherapy, throughout treatment and for two weeks post treatment. Patients will also perform standard of care skin treatment.
- interventionNames
- Other: Aveeno cream
- Other: Flamazine cream
- Other: NeoVIDERM cream
- type
- ACTIVE_COMPARATOR
- label
- Arm A: standard skin care
- description
- Patients will be asked to apply Aveeno cream twice a day starting the day of their treatment until two weeks after the end of their treatments. If they develop dry desquamation, they will be asked to apply Flamazine twice a day until dermatitis resolves.
- interventionNames
- Other: Aveeno cream
- Other: Flamazine cream
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria: For patients receiving radiation to the breast 1. Patients receiving a dose of at least 50 Gy in 25 fractions with concomitant chemotherapy or treated with the McGill technique. 2. Patients able to understand and sign an informed consent form. 3. Patients that do not have active connective tissue disorders. 4. Patients 18 years or older. 5. Patients that did not receive any previous radiation. 6. Patients that do not have any known allergy to any ingredients of the NeoVIDERM cream 7. Patients need to be able to apply the creams themselves or have help with applying the creams. Inclusion criteria: For patients receiving radiation to the head and neck 1. Patients receiving radiotherapy on fields that include both sides of the neck 2. Patients able to understand and sign an informed consent form. 3. Patients that do not have active connective tissue disorders. 4. Patients 18 years or older. 5. Patients that did not receive any previous radiation. 6. Patients that do not have any known allergy to any ingredients of the NeoVIDERM cream 7. Patients need to be able to apply the creams themselves or have help with applying the creams. Exclusion criteria: For patients receiving radiation to the breast or the head and neck 1. Patients that have a type V or type VI skin type according to the Fitzpatrick scale (because these patients will likely have less radiodermatitis and if they do, it will be harder to evaluate it). The Fitzpatrick Scale: * Type I (scores 0-7) White; very fair; freckles. Always burns, never tans * Type II (scores 8-16) White; fair. Usually burns, tans with difficulty * Type III (scores 17-25) Beige; very common. Sometimes mild burn, gradually tans * Type IV (scores 25-30) Beige with a brown tint; typical Mediterranean Caucasian skin. Rarely burns, tans with ease * Type V (scores over 30) Dark brown. Very rarely burns, tans very easily * Type VI Black. Never burns, tans very easily 2. Allergic to any ingredient in Neoviderm cream
References
Publications (0)
Data not yet available
No reference posted for this study.