Clinical trial · Interventional
Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging
Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging: Peritumoral Glial Cell Infiltration Quantitative Method
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will examine the use of a variation of standard magnetic resonance imaging (MRI) called diffusion tensor MRI (DT-MRI), in order to evaluate the peripheral white matter infiltration of high grade brain tumors. Organized architecture is destroyed once brain tumor cells are infiltrating surrounding tissue. The infiltrated tissue is then isotropic (or less anisotropic). DT-MRI can assess anisotropy after datasets post treatment. Primary outcome is to find if a correlation exists between GA (generalized anisotropy) and the infiltration percentage of stereotactic peritumoral biopsies.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| High Grade Brain Tumor | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| peritumoral glial cell infiltration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- brain tumor
- interventionNames
- Other: peritumoral glial cell infiltration
Primary outcomes (1)
- measure
- DTI-MRI
- timeFrame
- at J0
Secondary outcomes (3)
- measure
- Biopsy
- timeFrame
- at J+1
- measure
- count cell
- timeFrame
- at J+10
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: \- Patients with high grade brain tumor * Age greater than 18 yo and under 85 yo * Signed informed consent from patient Exclusion Criteria: * -Any person with pacemaker, metal implant, claustrophobia, or any other contraindication for MR examination * Severe renal failure * Brain tumor biopsy contraindication
References
Publications (0)
Data not yet available