Clinical trial · Interventional
Endoscopic Abraxane Injection Into Pancreatic Cysts
EUS Guided Injection of Albumin Bound Paclitaxel Into Pancreatic Cysts
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): expiration of IRB approval
Summary
Brief summary (as posted)
This research study is a pilot study. In this pilot study we are testing the safety of a procedure. "Investigational" means that the Albumin bound paclitaxel (Abraxane) is still being studied and that research doctors are trying to find out more about it. It also means that the FDA has not approved Abraxane injection for your type of medical condition. Treatment of pancreatic cysts often requires follow-up imaging studies and surgical resection of the cysts. As part of standard medical care, you will be undergoing a diagnostic endoscopic ultrasound guided fine needle aspiration (EUS-FNA) in order to evaluate type of the cyst. During the EUS and just after the cyst fluid aspiration, you will undergo the injection of the drug into the cyst cavity if your cyst is thought to be cancerous or precancerous. Cyst fluid will be analyzed for further diagnosis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cysts | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Albumin bound paclitaxel | Drug | Nab-paclitaxel | ALIAS |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Albumin bound paclitaxel
- description
- Albumin bound paclitaxel will be administered into the mucinous cyst of pancreas in endoscopy procedure.
- interventionNames
- Drug: Albumin bound paclitaxel
Primary outcomes (1)
- measure
- Frequency of Pancreatitis
- timeFrame
- 3-10 months (median 6 months) after injection therapy
- description
- Safety of injection of albumin-bound paclitaxel will be measured by the frequency of pancreatitis.
Secondary outcomes (2)
- measure
- Feasibility of Endoscopic Ultrasonography (EUS) Guided Injection of Albumin-bound Paclitaxel Into Pancreatic Cysts
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Mucinous cysts (premalignant or malignant cysts of the pancreas) * Normal organ and marrow function * Baseline CT within 6 months of enrollment Exclusion Criteria: * Pregnant or breastfeeding * Acute active pancreatitis * Complicated pancreatic cysts * Subjects who do not speak English
References
Publications (0)
Data not yet available