A Multi-centre Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)

Inclusion Criteria:

* Patient's written informed consent must be obtained prior to inclusion.
* Male or female outpatients or inpatients aged 40 to 80 years with an indication for complete colonoscopy.
* Willing to undergo a colonoscopy for diagnostic or surveillance purposes
* Patients with a known personal of familial risk of colon neoplasia, willing to undergo a screening colonoscopy
* Willing, able and competent to complete the entire procedure and to comply with study instructions.
* Females of childbearing potential must employ an adequate method of contraception.

Exclusion Criteria:

* History of gastric emptying disorders.
* History of ileus, toxic megacolon, gastrointestinal obstruction and colonic perforation.
* History of phenylketonuria.
* Known glucose-6-phosphate dehydrogenase deficiency.
* Known hypersensitivity to macrogol 3350, sodium sulphate or ascorbic acid/sodium ascorbate.
* History of colonic resection.
* Requirement for permanent medication and associated stable serum concentrations (e.g. neuroleptic drugs).
* Presence of congestive heart failure (NYHA III + IV).
* Acute life-threatening cardiovascular disease.
* Documented history of severe renal insufficiency (creatinine clearance \<30 ml/min).
* Other contraindication described in the summary of product characteristics (SmPC) of either preparation.
* Patient has a condition, clinically significant laboratory results, or is in a situation which, in the investigator's opinion, may put the patient at significant risk, may confound the study results, or may interfere significantly.
* Application of any unlicensed medication within the previous 3 months or participation in any other research study in the last 3 months.
* Females who are pregnant, nursing or planning a pregnancy.
* Patients who, in the opinion of the investigator, may not be compliant with the study requirements.
* Previous participation in this clinical study.