A Study in Participants With Advanced Solid Tumors

Inclusion Criteria:

* Chinese participants with histopathologically or cytologically diagnosed advanced solid tumor
* Did not respond to standard therapy or no standard therapy is available
* Measurable or nonmeasurable disease according to the Response Evaluation Criteria In Solid Tumors (RECIST)
* Eastern Cooperative Oncology Group (ECOG) performance status score of 0-1 at study entry
* Able to provide written informed consent
* A life expectancy of \>3 months
* Adequate hematologic function, as defined by: Absolute neutrophil count (ANC) ≥1500 per cubic millimeter (mm\^3); hemoglobin concentration ≥9 grams per deciliter (g/dL); and platelet count ≥100,000/mm\^3
* Adequate hepatic function, as defined by: Total bilirubin level ≤1.5 x the upper limit of normal (ULN) (in participants with known Gilbert Syndrome, a total bilirubin ≤ 3.0 x ULN with direct bilirubin ≤ 1.5 x ULN); aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤2.5 x ULN (or ≤5 x ULN if the participant has liver metastases
* Adequate renal function, as defined by: Serum creatinine level ≤1.5 x ULN; or calculated serum creatinine clearance (Cockcroft-Gault) ≥50 milliliters per minute (mL/min)
* Urinary protein is 0 or 1+ on dipstick but no edema nor serum albumin \< lower level of normal
* Adequate coagulation function, as defined by: International normalized ratio (INR) ≤1.5, or prothrombin time (PT) ≤1.5 x ULN and activated partial thromboplastin time (aPTT) ≤1.5 x ULN (unless receiving anticoagulation therapy)
* Agrees to use adequate contraception during the study period and for 12 weeks after the last dose of study treatment

Exclusion Criteria:

* Had chemotherapy or therapeutic radiotherapy within 14 days (6 weeks for nitrosoureas or mitomycin C) before entering the study or the participant has ongoing side effects (≥ Grade 2) due to previously administered agents
* Has obvious evidence of intratumor cavitation
* Has undergone major surgery within 28 days before study entry or has had a central venous access device inserted within 7 days before study entry
* Has a history of gastrointestinal perforation, postoperative bleeding complications, or wound complications from a surgical procedure
* Has elective or planned surgery to be conducted during the trial
* Has documented and/or symptomatic brain or leptomeningeal metastases
* Has uncontrolled ongoing illness, for example: thrombotic or hemorrhagic disorders; hemoptysis; ongoing infection requiring systemic antibiotic treatment; congestive heart failure, angina pectoris, angioplasty, stenting, or myocardial infarction within 6 months; stroke, transient ischemic attack (TIA), or other grade 3-4 arterial thromboembolic event occurring within 6 months; uncontrolled hypertension (≥150/≥90 millimeters of mercury \[mmHg\]); cardiac arrhythmia that requires treatment or asymptomatic sustained ventricular tachycardia; peripheral neuropathy ≥Grade 2; human immunodeficiency virus (HIV) or active, uncontrolled hepatitis, liver cirrhosis at a level of Child-Pugh Class B (or worse), liver cirrhosis (any degree) and a history of hepatic encephalopathy or clinically meaningful ascites resulting from cirrhosis. (Clinically meaningful ascites is defined as ascites resulting from cirrhosis and requiring ongoing treatment with diuretics and/or paracentesis)
* Has a serious or nonhealing wound, ulcer, or bone fracture within 28 days before study entry
* Has experienced any Grade 3 or 4 gastrointestinal bleeding within 3 months before study entry
* Has a history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess \<6 months before randomization, or the participant has a history of poorly controlled or recurrent inflammatory bowel disease (including Crohn's disease or ulcerative colitis)
* Has participated in a clinical study of a non-approved experimental agent or procedure within 4 weeks prior to study entry for small molecules, or 8 weeks before study entry for non-approved monoclonal antibodies
* Has a known allergy to ramucirumab or its excipients, a monoclonal antibody (MAb), or any other therapeutic protein, such as fresh frozen plasma, human serum albumin (HSA), cytokines, or interleukins. If there is suspicion that the participant may have an allergy, the participant should be excluded
* Is pregnant (confirmed by urine or serum pregnancy test) or lactating
* Has known alcohol or drug dependency
* Is receiving chronic therapy with nonsteroidal anti-inflammatory agents (NSAIDs)
* Is not considered to be suitable for this study, in the opinion of the investigator