Clinical trial · Observational
Survey on Chinese Medicine Syndrome for Patients With Non Small Cell Lung Cancer
The Changing Pattern of Chinese Medicine Syndrome for Patients With Non Small Cell Lung Cancer in Hong Kong: A Longitudinal Survey
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Inability to recruit adequate number of patients
Summary
Brief summary (as posted)
Lung cancer has been the leading cancer worldwide, which can be divided into small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) based on biology, therapy, and prognosis. NSCLC accounts for more than 85% of all lung cancer cases and has a poor prognosis with only 15% of all lung cancer patients alive 5 years or more after diagnosis. Traditional Chinese medicine (TCM) originated from Chinese philosophy is a different medical system from conventional western medicine. It focuses on health maintenance and emphasizes on harmonizing the imbalance of body. Current studies show that TCM has the advantages of increasing the sensitivity of chemo- and radio-therapeutics, reducing the side effects and chemo- and radio-therapeutics associated complications, improving patients' quality of life and survival time. However, how TCM can work with conventional medicine for the treatment of carcinoma is still an important research topic worldwide. Syndrome, the essential concept in TCM theory, is a diagnostic conclusion of the pathological changes at a certain stage of a disease, including the location, cause, and nature as well as the trend of development. This study aims to investigate the distribution of TCM syndromes, the changing pattern among NSCLC patients before and after having surgery, chemotherapy and radiation therapy, and the correlations with patient quality of life and progression free survival. The results are important for establishing guidelines for TCM practice and research in future.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- NSCL cancer patients
- description
- Surgery, chemotherapy and/or radiation therapy
Primary outcomes (1)
- measure
- Changes of TCM syndromes
- timeFrame
- Baseline (Pre-operation) and 1 week (Post-operation)
Secondary outcomes (3)
- measure
- Changes of TCM syndromes
- timeFrame
- Baseline, Post chemotheray/radiation therapy, 3rd month, 6th month, 9th month, 12th month, 15th month, 18th month, 21month, 24month
- measure
- QoL assessment
- timeFrame
- Post operation therapy, Post chemotheray/radiation therapy, 3rd month, 6th month, 9th month, 12th month, 15th month, 18th month, 21month, 24month
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria: * newly suspected / diagnosed NSCLC patients from Department of Cardiothoracic Surgery and going to have resection * age of 18 or above * without prior therapy for NSCLC, including surgery, chemotherapy, radiation therapy and Chinese herbal medicine * patients who can read and speak Chinese Exclusion criteria: * history of prior therapy for NSCLC * history of concurrent or prior malignancy * with concurrent open tuberculosis or inflection * unable to communicate (e.g. cognitive impairment) * psychiatric or addictive disorders
References
Publications (0)
Data not yet available