Clinical trial · Interventional
Feasibility Study of Laparoendoscopic Single Site Surgical Staging for Endometrial Cancer
Prospective Randomized Comparison of Single-port and Four-port Laparoscopic Staging Operation for Endometrial Cancer
NCT01679522CI-TRIAL-00062395LESS-EcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To compare the feasibility, safety, and efficacy between single-port and four-port laparoscopic surgical staging in patients with early stage endometrial cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Four-port laparoscopic surgical staging | Procedure | — | UNRESOLVED |
| single-port laparoscopic surgical staging | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Single-port surgery group
- description
- Single-port laparoscopic surgical staging including total hysterectomy, pelvic lymph node dissection, and/or bilateral salpingooophorectomy, and/or para-aortic lymph node dissection
- interventionNames
- Procedure: single-port laparoscopic surgical staging
- type
- ACTIVE_COMPARATOR
- label
- Four-port surgery group
- description
- Four-port laparoscopic surgical staging including total hysterectomy, pelvic lymph node dissection, and/or bilateral salpingooophorectomy, and/or para-aortic lymph node dissection
- interventionNames
- Procedure: Four-port laparoscopic surgical staging
Primary outcomes (2)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Previously untreated, histologically confirmed endometrial cancer * Presumed FIGO stage 1 * Endometrioid adenocarcinoma * patient who is planned to undergo surgical staging * adequate oran function 1. WBC \> 3000 cells/mcl 2. Platelets \> 100000/mcl 3. Creatinine \< 2.0 mg/dL 4. Bilirubin \< 1.5 \* normal and SGOT or SGPT \< 3 \* normal * American Society of Anesthesiologists Physical Status I-II * Eastern Cooperative Oncology Group performance status 0-2 * Patients who have signed an approved Informed Consent Exclusion Criteria: * Uncontrolled medical disease * Active infectious disease requiring antibiotics * Previous pelvic radiation therapy * Pregnant and lactating woman * Patient who requires additional surgical procedures which are not necessary for surgical staging of endometrial cancer
References
Publications (1)
- DERIVEDKang OJ, Nam JH, Park JY. Laparo-endoscopic single-site versus conventional laparoscopic surgery for early-stage endometrial cancer: A randomized controlled non-inferiority trial. Gynecol Oncol. 2023 Jun;173:74-80. doi: 10.1016/j.ygyno.2023.04.005. Epub 2023 Apr 25. PMID 37105060