Clinical trial · Observational
An Observational Study of Avastin and Conventional Chemotherapy in Patients >/= 70 Years of Age With Previously Untreated Metastatic Colorectal Cancer (AVAPLUS)
Prospective Non-interventional Study to Collect Data on the Use of Avastin and Conventional Chemotherapy for the Treatment of Previously Untreated Metastatic Colorectal Cancer in Patients >/= 70 Years
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study will evaluate the use of Avastin (bevacizumab) and conventional chemotherapy in patients \>/= 70 years of age with previously untreated metastatic colorectal cancer. Data will be collected from each patient from initiation of treatment until disease progression occurs (minimum follow-up 12 months).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Cohort
Primary outcomes (1)
- measure
- Treatment duration in patients receiving chemotherapy with Avastin as first-line therapy in daily clinical practice
- timeFrame
- approximately 24 months
Secondary outcomes (5)
- measure
- Treatment duration in patients receiving chemotherapy alone as first-line therapy in daily clinical practice
- timeFrame
- approximately 24 months
- measure
- Safety: Incidence of adverse events/adverse events of special interest
- timeFrame
- approximately 24 months
- measure
- Clinical/demographic patient characteristics at baseline
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients, \>/ 70 years of age * Previously untreated metastatic colorectal cancer * Patient considered suitable to receive chemotherapy with or without Avastin Exclusion Criteria: * Participation in any other clinical trial or study with the exception of participation in registries
References
Publications (0)
Data not yet available