Clinical trial · Interventional
Comparison Between Posterior Retroperitoneoscopic Adrenalectomy and Laparoscopic Adrenalectomy
Randomized Controlled Trial Between PRA(Posterior Retroperitoneoscopic Adrenalectomy) and LA(Laparoscopic Adrenalectomy)
NCT01676025CI-TRIAL-00029806PRAcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare two surgical methods of adrenalectomy. One is called PRA(posterior retroperitoneal adrenalectomy), which is performed through 3 or 4 holes at patient's back. The other is LA(laparoscopic adrenalectomy) which is performed through patient's abdominal cavity after making 3 or 4 holes in the abdomen.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adrenal Disease | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LA | Procedure | — | UNRESOLVED |
| PRA | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PRA
- description
- Persons who get PRA surgery.
- interventionNames
- Procedure: PRA
- type
- EXPERIMENTAL
- label
- LA
- description
- Persons who get LA surgery.
- interventionNames
- Procedure: LA
Primary outcomes (1)
- measure
- Operation time
- timeFrame
- Participants will be followed until the first visit of out patients clinic after discharge, an expected average of 3 weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who are expected to have benign adrenal disease at preoperative exams * Patients who have pheochromocytoma measured less than 5cm, and the other benign adrenal tumors less than 7cm in diameter in preoperative CT scan * Patients who do not have previous surgery history at the interested quadrant * Patients who is I or II grade in ASA classification(American society of anesthesiologists' physical status classification) * Patients who has tolerable liver function and renal function(bilirubin\<2.0mg/dl and AST, ALT, serum creatinine within twice of upper normal range, coagulation panel : within normal limit) * Patients whose BMI(body mass index) is less than 35 * Patients who are supposed to have normal cognitive function * Patients who signed the consent paper. Exclusion Criteria: * Patients who are expected to have malignant or metastatic adrenal tumor at preoperative exams * Patients who have bilateral adrenal tumors * Patients who have condition to undergo the other operation at the abdomen together with adrenalectomy * Pregnant patients * Patients who have active or uncontrolled infection * Patients who have medical problems as below * Uncontrollable hypertension with medication(Systolic BP\>150 or diastolic BP\>100) * Angina, congestive heart failure, acute myocardial infection * History of coronary angioplasty or Coronary artery bypass graft surgery * History of stroke, transient ischemic attack with sequela
References
Publications (1)
- DERIVEDChai YJ, Yu HW, Song RY, Kim SJ, Choi JY, Lee KE. Lateral Transperitoneal Adrenalectomy Versus Posterior Retroperitoneoscopic Adrenalectomy for Benign Adrenal Gland Disease: Randomized Controlled Trial at a Single Tertiary Medical Center. Ann Surg. 2019 May;269(5):842-848. doi: 10.1097/SLA.0000000000002603. PMID 29189215