Clinical trial · Interventional
Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion
NCT01670786CI-TRIAL-00014493completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Iodopovidone is safe when using as a pleurodesis sclerosing agent for malignant pleural effusion, with minimal adverse events, especially reducing dose.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pleural Effusion, Malignant | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pleurodesis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Iodopovidone 1%
- description
- The patients enrolled in this arm were submitted to pleurodesis with iodopovidone 1% administration into pleural cavity.
- interventionNames
- Procedure: pleurodesis
- type
- EXPERIMENTAL
- label
- Iodopovidone 2%
- description
- The patients enrolled in this arm were submitted to pleurodesis with iodopovidone 2% administration into pleural cavity.
- interventionNames
- Procedure: pleurodesis
Primary outcomes (1)
- measure
- Safety of iodopovidone as an agent for pleurodesis
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * malignant pleural effusion * Recurrent pleural effusion * Complete lung expansion (\> 80%) after puncture emptying confirmed by chest radiography. * Karnofsky index \> 40. * Agreed to participate in the study and sign an Informed Consent Exclusion Criteria: * Thrombocytopenia or coagulation disorders * Patients with impaired renal function * Pleural or active systemic infection * Massive neoplastic infiltration of the skin * Inability to understand the quality of life questionnaire * Previous pleural procedures * Allergy to iodine * Thyroid disorders
References
Publications (0)
Data not yet available
No reference posted for this study.